Probing the Diversity of T Cell Dysfunction in Cancer
نویسندگان
چکیده
T cell dysfunction in cancer comes in many forms, with two new varieties reported in this issue. Daley et al. find that T cells expressing γδ T cell receptors (TCR) promote pancreatic tumor growth by inhibiting activation of T cells with conventional TCRs. Singer et al. characterize dysfunctional tumor infiltrating lymphocytes to reveal a role for zinc homeostasis in anti-tumor immunity.
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عنوان ژورنال:
- Cell
دوره 166 شماره
صفحات -
تاریخ انتشار 2016